Lonzabonemarrowmononuclearcells
Bonemarrow mononuclearcells(commonabbreviations:BMNC,BMMNC,andBM-MNC)areamixedpopulationofsinglenucleuscellsincludingmonocytes,lymphocytes,andhematopoieticstemandProgenitorcells.
BMNCsYouCanCountontoPerform
CryopreservedLonzaBoneMarrowMononuclearCellsareisolatedfromwholebonemarrowviadensitygrADIentseparation.Isolatingmononuclearcellseliminateserythrocytesandgraulocytes,producingamorestablecellproduct.
LonzaBMNCsareavailablefreshorfrozenfromalargeandvarieddonorpool.Theyareguaranteedtocontaineither≥5,25,100,or200millionviablecellsperampoule,dependinguponproductpurchased.
FreshcellsaresUSPendedinHBSSwith5mMEDTAand0.5%BSAandareavailable inavarietyof cellspervialpackagingsizes.FreshBMNCorders requireaminimumorder quantityoftwovialsperdonor.PleasecontactCustomerServiceforinformationonsizesandpricingforfreshcells.
ChoicesinCellTypeandTissueSource
Lonzaofferschoicesincelltypeandtissuesourcesoyoucanchoosetherightproductforyourresearchandbudgetneeds.Dependinguponyourultimatecellofchoice,youcanchoosefromunprocessedbonemarrow,bonemarrowMNCs,bonemarrowCD34+cells,bonemarrowCD133+cells,bonemarrowstromalcells(foruseasfeedercells),orbonemarrowmesenchymalstemcells.Inaddition,ifbonemarrowisnotyourpreferredtissuesource,wealsooffercordbloodderivedcells.
SupportedbyanOptimizedCultureSystem
HPGM™HematopoieticGrowthMediumisrecommendedforoptimalperformanceinserum-freeculturing(additionalcytokinesmaybenecessarydependingonapplication).Alternativemediacontainingserummayalsobeacceptable.PleasecontactScientificSupportforserumcontainingmediarecommendations.
LonzaguaranteestheperformanceofClonetics™/Poietics™cellsonlyifappropriateClonetics™/Poietics™mediaandreagentsareusedexclusivelyandtherecommendedstorageanduseprotocolsarefollowed.Anymodificationsmadetotherecommendedcellsystemsincludingtheuseofalternativemedia,reagentsorprotocols,willvoidcellandmediaperformanceguarantees.Ifyouneedassistanceinselectingtheappropriatemedia,reagents,orprotocol,pleasecontactLonzaScientificSupport.
Minimumorderquantityof2vialsperdonorisrequiredforfreshcells.HIV-1,hepatitisBandhepatitisCarenotdetectedforalldonorsand/orcelllots.ACertificateofAnalysisisprovidedforeachcelllotpurchased.